Dibenzocyclooctyne-amine: A Leaders' Choice in Copper-free Click Chemistry
Short description
Dibenzocyclooctyne-amine (DBCO-NH2) is an indispensable compound in bioconjugation, material science, and drug discovery. Key details include:
- CAS No.: 1255942-06-3
- Linear and Empirical Formula: C18H16N2O
Dubbed DBCO-amine, this compound exhibits unique reactivity with azides, critical for connecting diverse molecules reliably and efficiently. It propels copper-free click chemistry by eliminating the need for a catalytic reaction and reducing cytotoxicity. These traits amplify its value in biochemical applications and make it an uber-effective tool in the scientific arena.
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India
2025 years
Description
Dibenzocyclooctyne-amine: Unleashing the Potential of Copper-free Click Chemistry
As an essential player in the domain of copper-free click chemistry, Dibenzocyclooctyne-amine, other times referred to as DBCO-NH2 or DBCO-amine, exemplifies its beauty in multiple scientific pursuits. The compound bears a CAS number of 1255942-06-3 and the molecular and empirical formula of C18H16N2O. It finds its niche in bioconjugation studies and permeates through various applications including, but not limited to, biomolecule labelling, synthesis of drug delivery systems, and creation of gene delivery vectors.
Distinctive Features
- High Purity: Experience consistent and reliable experimental outcomes with the pure form of Dibenzocyclooctyne-amine.
- Superior Stability: The compound offers outstanding stability, enabling long-term storage and usability with negligible degradation.
- Optimal Efficiency: Accelerate your copper-free click chemistry reactions with the high reactivity of Dibenzocyclooctyne-amine.
- Wide Compatibility: Unleash its universal potential, as it partners with various azides and alkynes, enriching its applicability in diverse research territories.
- User-friendly: Save those crucial preparation steps as the easy-to-handle compound comes ready for use.
Applications
- Ligand Labelling: Labelling proteins, peptides, oligonucleotides, and other biomolecules with functional groups, tags, or fluorophores has never been easier.
- Drug Delivery Strategies: Aid in the construction of precise drug delivery systems like polymeric nanoparticles, micelles, and liposomes for targeted drug delivery.
- Bioorthogonal Chemistry Applications: Employ it in bioorthogonal chemistry to explore complex biological activities and selectively label biomolecules.
- Click-to-Probe Strategies: Enable visualization and imaging of specific biomolecules or cellular structures by devising click-to-probe techniques.
- Gene Delivery Architectures: Assist in the development of efficient gene delivery vectors for performing various applications, including genome editing and gene therapy.
Safety Guidelines
Tread with caution while handling Dibenzocyclooctyne-amine. Adhere to standard laboratory practices, wear protective clothing, gloves, and eyewear. For elaborate safety instructions, handling procedures, storage, and disposal, refer to the corresponding Material Safety Data Sheet (MSDS).
